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Academic History |
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1980-1984 |
B.A., Chemistry; Honors; The Johns Hopkins University |
1981-1984 |
Summer Research Scientist
Airco Central Research Laboratory, Murray Hill, N.J. |
1983-1984 |
Undergraduate Research Fellow, Organic Synthesis
The Johns Hopkins University, Advisor: Professor Alex Nickon. |
1984-1989 |
Ph.D., Biophysical Chemistry; University of California, Berkeley |
1984-1989 |
Research Assistant, University of California, Berkeley
Advisor: Professor Ignacio Tinoco Jr. |
1989-1991 |
Postdoctoral Fellow; EMBO Postdoctoral Fellowship
I.B.M.C du CNRS, Strasbourg, France. Advisor: Richard Giegé |
1991-1993 |
Postdoctoral Fellow, Department of Chemistry
Massachusetts Institute of Technology, Cambridge, MA
Advisor: James R. Williamson. |
1993-1997 |
Affiliated Faculty, Molecular, Cellular, & Developmental Biology
Graduate Program, Department of Biology
University of California, Santa Cruz. |
1993-1997 |
Assistant Professor, Department of Chemistry and Biochemistry
University of California, Santa Cruz |
1997-1997 |
Associate Professor, Department of Chemistry and Biochemistry
University of California, Santa Cruz |
1997-2004 |
Associate Professor, Department of Structural Biology
Stanford University School of Medicine, Stanford, CA |
1997-present |
Director, Stanford Magnetic Resonance Laboratory (SMRL) |
1998-2004 |
Associate Chair, Department of Structural Biology |
2004-present |
Chair, Department of Structural Biology |
2004-present |
Professor, Department of Structural Biology
Stanford University School of Medicine, Stanford, CA |
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Teaching Experience |
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U.C. Berkeley |
Summer 1989, "Introductory Chemistry" |
U.C. Santa Cruz |
Winter 1994, 1996, Fall 1994, "Advanced Biochemistry: Nucleic Acid Structure and Function" |
U.C. Santa Cruz |
Spring 1994, 1995, 1996, "Physical Chemistry Principles" |
U.C. Santa Cruz |
Fall, 1995, 1996, "Introductory Chemistry" |
Stanford University |
Fall, 1998, 1999, 2000, 2001, Histology (three lectures per quarter); Fall 1998, 1999, "Structural Principles of Proteins and Nucleic Acids"; Fall 2000, 2001, Structural Biology/Biochemistry 241, "Biological Macromolecules"; Winter 2001, Structural Biology 242, "Methods in Molecular Biophysics" |
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Professional Societies and Awards |
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1984-1985 |
Department of Chemistry, Berkeley, Bruce Mahan Memorial Teaching Award |
1987 |
Outstanding Graduate Teaching Assistant |
1988 |
Department of Chemistry, Berkeley, Bruce Mahan Memorial Teaching Award |
1989 |
Sigma Xi Honor Society |
1989 |
Thesis nominated for J.T. Baker Award in Chemistry |
1993 |
Camille and Henry Dreyfus Teacher-Scholar Award |
1994 |
David and Lucille Packard Fellowship in Science and Engineering |
1997 |
Alfred P. Sloan Research Fellow |
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Current Collaborative Research |
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Steve Chu |
Single molecucule analysis of protein synthesis by the ribosome |
Roger Kornberg |
Attempting to study the ribosome using electron microscopy |
Peter Sarnow |
Joint Stanford support to study the structure and function of the Hepatitis C internal |
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Publications |
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| 81 |
"Peptide bond formation destabilizes Shine-Dalgarno interaction on the ribosome," Uemura S, Dorywalska M, Lee TH, Kim HD, Puglisi JD, Chu S |
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Nature, 2007, 446(7134), 454-7 |
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| 80 |
"Molecular framework for the activation of RNA-dependent protein kinase," McKenna SA, Lindhout DA, Kim I, Liu CW, Gelev VM, Wagner G, Puglisi JD |
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J. Biol. Chem., 2007 Feb 6, [Epub ahead of print], |
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| 79 |
"Rapid purification of RNAs using fast performance liquid chromatography (FPLC)," Kim I, McKenna SA, Viani Puglisi E, Puglisi JD |
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RNA, 2007, 13(2), 289-94 |
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| 78 |
"Uncoupling of RNA Binding and PKR Kinase Activation," Sean A. McKenna, Insil Kim, Corey W. Liu and Joseph D. Puglisi |
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J. Mol. Biol., 2006, 358, 1270-1285 |
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| 77 |
"Specific Recognition of HIV TAR RNA by the dsRNA Binding Domains (dsRBD1-dsRBD2) of PKR," Kim I, Liu CW, and Puglisi JD |
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J. Mol. Biol., 2006, 358, 430-442 |
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| 76 |
"Quantitative polysome analysis identifies limitations in bacterial cell-free protein synthesis," Kelly A. Underwood, James R. Swartz, Joseph D. Puglisi |
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Biotechnology & Engineering, 2005, 91, No. 4, 425-35 |
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| 75 |
"Structure Determination of Large Biological RNAs," Lukavsky PJ, Puglisi JD |
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Methods Enzymol., 2005, 394, 399-416 |
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| 74 |
"Site-specific labeling of the ribosome for single-molecule spectroscopy," Dorywalska M, Blanchard SC, Gonzalez RL, Kim HD, Chu S, Puglisi JD |
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Nucleic Acids Res., 2005, 33(1), 182-9 |
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| 73 |
"The Pathway of HCV IRES-Mediated Translation Initiation," Geoff A. Otto and Joseph D. Puglisi |
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Cell, 2004, 119, 369-380 |
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| 72 |
"tRNA selection and kinetic proofreading in translation," Blanchard SC, Gonzalez RL, Kim HD, Chu S, Puglisi JD |
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Nat. Struct. Mol. Biol., 2004, 11(10), 1008-14 |
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| 71 |
"tRNA dynamics on the ribosome during translation," Blanchard SC, Kim HD, Gonzalez RL Jr, Puglisi JD, Chu S |
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Proc. Natl. Acad. Sci. U.S.A., 2004, 101, 12893-12898 |
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| 70 |
"Large-scale preparation and purification of polyacrylamide-free RNA oligonucleotides," Lukavsky PJ, Puglisi JD |
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RNA, 2004, 10(5), 889-893 |
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| 69 |
"Design of a cyclic peptide that targets a viral RNA," Runyon ST, Puglisi JD |
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J. Am. Chem. Soc., 2003, 125(51), 15704-5 |
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| 68 |
"Thermodynamic stability and structural features of the J4/5 loop in a Pneumocystis carinii group I intron," Schroeder SJ, Fountain MA, Kennedy SD, Lukavsky PJ, Puglisi JD, Krugh TR, Turner, DH |
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Biochemistry, 2003, 42(48), 14184-96 |
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| 67 |
"Structure of HCV IRES domain II determined by NMR," Peter J Lukavsky, Insil Kim, Geoff A Otto & Joseph D. Puglisi |
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Nature Structural Biol., 2003, Advance Online Publication |
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| 66 |
"Solution structure and backbone dynamics of the holo form of the frenolicin acyl carrier protein.," Li Q, Khosla C, Puglisi JD, Liu CW. |
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Biochemistry, 2003, 42(16), 4648-57 |
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| 65 |
"Comparison of x-ray Crystal Structure of the 30s Subunit-Antibiotic Complex with NMR Structure of Decoding Site Oligonucleotide-Paromomycin Complex," Lynch, S.R., Gonzalez, R.L., and Puglisi, J.D. |
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Structure, 2003, 11, 43-53 |
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| 64 |
"NMR Study of 100 kDa HCV IRES RNA Using Segmental Isotope Labeling," ˇ Kim, I., Lukavsky, P.J., and Puglisi, J.D. |
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J. Am. Chem. Soc., 2002, 124, 9338-39 |
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| 63 |
"Ribosomal proteins mediate the hepatitis C virus IRES-HeLa 40S interaction.," ˇ Otto, G.A., Lukavsky, P.J., Lancaster, A.M., Sarnow, P. and Puglisi, J.D. |
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RNA, 2002, 8, 913-923 |
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| 62 |
"Sequence-Specific Recognition of the Major Groove of RNA by Deoxystreptamine.," Yoshizawa, S., Fourmy, D., Eason, R.G., and Puglisi, J.D. |
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Biochemistry, 2002, 41, 6263-70 |
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| 61 |
"RNAPack - An integrated NMR approach to RNA structure determination.," Lukavsky, P. J. and Puglisi, J. D. |
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Methods, 2001, 25, 316-332 |
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| 60 |
"Aminoglycoside Resistance with Homogeneous and Heterogeneous Populations of Antibiotic-Resistant Ribosomes.," Recht, M. I. and Puglisi, J. D |
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AAC, 2001, 45, 2414-19 |
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| 59 |
"Solution structure of the A loop of 23S ribosomal RNA," Blanchard, S.C., and Puglisi, J.D. |
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Proc. Natl. Acad. Sci. U.S.A., 2001, 98(7), 3720-21 |
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| 58 |
"Structural origins of aminoglycoside specificity for prokaryotic ribosomes.," Lynch, S.R., and Puglisi, J.D. |
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J. Mol. Biol. , 2001, 306, 1037-58 |
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| 57 |
"Structure of a Eukaryotic Decoding Region A-site RNA ," Lynch, S.R., and Puglisi, J.D. |
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J. Mol. Biol. , 2001, 306, 1023-1035 |
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| 56 |
"Structures of two RNA domains essential for hepatitis C virus internal ribosome entry site function," Lukavsky, P.J., Otto, G.A., A.M. Lancaster, A.M., Sarnow, P. and Puglisi, J.D. |
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Nature Structural Biol.,, 2000, 7, 1105-1110 |
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| 55 |
"Approaching translation at atomic resolution," Puglisi, J. D., Blanchard, S. C., & Green |
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Nature, 2000, 7, 855-861 |
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| 54 |
"Application of Residual Dipolar Coupling Measurements to Identify Conformational Changes in RNA Induced by Antibiotics," Lynch, S. and Puglisi, J.D. |
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J. Am. Chem. Soc., 2000, 122, 7853-7854 |
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| 53 |
"Interaction of Translation Initiation Factor IF1 with the E. coli ribosomal A site," Dahlquist, K. and Puglisi, J. D. |
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J. Mol. Biol., 2000, 299, 1-15 |
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| 52 |
"mRNA processing: The 3'-end justifies the means," Puglisi, J.D. |
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Nature Struct. Biol., 2000, 4, 263-264 |
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| 51 |
"Aminoglycoside Antibiotics and Decoding," Puglisi, J. D., Blanchard, S. C., Dahlquist, K. D., Eason, R. G., Fourmy, D., Lynch, S., Recht, M. I., & Yoshizawa, S. |
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Ribosomes99, 1999, Chapter 34, 419-429 |
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| 50 |
"The ribosome revealed," Green, R. and Puglisi, J. D. |
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Nature Structural Biol., 1999, 6, 999-1004 |
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| 49 |
"RNA helix recognition by ribosomal RNA," Yoshizawa, S., Fourmy, D., & Puglisi, J. D. |
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Science, 1999, 285, 1722-1725 |
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| 48 |
"Basis for prokaryotic specificity of action of aminoglycoside antibiotics," Recht, M. I., Douthwaite, S., & Puglisi, J. D. |
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EMBO J., 1999, 18, 3133-3138 |
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| 47 |
"Biochemical and NMR studies of aminoglycoside-RNA complexes," Lynch, S. R., Recht, M. I. & Puglisi, J. D. |
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Methods in Enzymology, 2000, 317, 240-61 |
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| 46 |
"Effect of mutations in the A site of 16S rRNA on aminoglycoside antibiotic-ribosome interaction," Recht, M. I., Douthwaite, S., Dahlquist, K. D., & Puglisi, J. D. |
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J. Mol. Biol., 1999, 286, 33-43 |
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| 45 |
"RNA interaction with small ligands and peptides," Puglisi, J. D. & Williamson, J. R. |
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RNA World II, 1999, T. Cech & R. Gesteland, eds., pp 403-425 |
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| 44 |
"HIV-1 A-rich RNA loop mimics the tRNA anticodon structure," Puglisi, E. V. & Puglisi, J. D. |
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Nature Struct. Biol., 1998, 5, 1033-1036 |
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| 43 |
"Structural origins of gentamicin antibiotic action," Yoshizawa, S., Fourmy, D. & Puglisi, J. D. |
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EMBO J., 1998, 17, 6437-6448 |
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| 42 |
"NMR structure determination of an antibiotic-RNA complex," Yoshizawa, S. & Puglisi, J. D. |
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NATO ASI series., 1998, 301, 173-182 |
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| 41 |
"rRNA chemical groups required for aminoglycoside binding," Blanchard, S. C., Fourmy, D., Eason, R. G., & Puglisi, J. D. |
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Biochemistry, 1998, 37, 7716-7724 |
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| 40 |
"Binding of neomycin-class aminoglycoside antibiotics to the A-site of 16S rRNA," Fourmy, D., Recht, M. I., & Puglisi, J. D. |
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J. Mol. Biol., 1998, 277, 347-362 |
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| 39 |
"Paromomycin binding induces a local conformational change in the A site of 16S rRNA," Fourmy, D., Yoshizawa, S. & Puglisi, J. D. |
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J. Mol. Biol., 1998, 277, 333-345 |
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| 38 |
"Nuclear magnetic resonance spectroscopy of RNA," Puglisi, E. V. & Puglisi, J. D. |
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RNA Structure and Function, 1998, R. W. Simons & M. Grunberg-Manago, eds., pp. 117-146 |
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| 37 |
"Structural basis for aminoglycoside antibiotic action," Puglisi, J. D. |
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Many Faces of RNA, 1997, pp. 97-111 |
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| 36 |
"Structure of a conserved RNA component of the peptidyl transferase center," Puglisi, E. V., Noller, H. F., & Puglisi, J. D. |
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Nature Struct. Biol., 1997, 4, 775-778 |
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| 35 |
"RNA structure," Puglisi, E. Viani & Puglisi, J. D. |
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Post Transcriptional Gene Regulation, 1997, D. Morris & J. Harford, eds., N.Y. Wiley & sons, pp. 1-22 |
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| 34 |
"Structure of the A site of E. coli 16S rRNA complexed with an aminoglycoside antibiotic," Fourmy, D., Recht, M., Blanchard, S. D., & Puglisi, J. D. |
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Science, 1996, 274, 1367-1371 |
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| 33 |
"RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide," Recht, M., Fourmy, D., Blanchard, S., Dahlquist, K., & Puglisi, J. D. |
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J. Mol. Biol., 1996, 262, 421-436 |
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| 32 |
"Solution structure of an RNA-peptide complex," Puglisi, J. D., Chen, L., Blanchard, S., & Frankel, A. |
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Science:1995, 270, 1200-1203, |
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| 31 |
"Welcome guests to the RNA World: Proteins that interact with RNA," Puglisi, J. D. |
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Book Review Chemistry & Biology, 1995, 2, 581 |
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| 30 |
"Biochemical and NMR studies of RNA conformation," Puglisi, J. D. & Wyatt, J. R. |
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in Methods in Enzymology, 1995, 261, 323-350 |
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| 29 |
"NMR Analysis of tRNA acceptor stem microhelices: Discriminator base changes affect tRNA conformation at the 3'-end," Puglisi, E. V., Puglisi, J. D., Williamson, J. R., & RajBhandary, U. L. |
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Proc. Nat'l Acad. Sci. U. S. A., 1994, 91, 11467-11471 |
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| 28 |
"Role of RNA Structure in Arginine Binding to TAR RNA," Puglisi, J. D., Chen, L. Frankel, A. D., & Williamson, J. R. |
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Proc. Nat'l Acad. Sci. U. S. A., 1993, 90, 3680-3684 |
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| 27 |
"Additive, Cooperative and Anticooperative Effects between Identity Nucleotides of a tRNA," Pütz, J., Puglisi, J. D., Florentz, C., & Giegé, R. |
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EMBO J., 1993, 12, 2949-2957 |
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| 26 |
"Influence of tRNA Tertiary Structure and Stability on Aminoacylation by yeast Aspartyl-tRNA Synthetase," Puglisi, J. D., Pütz, J., Florentz, C., & Giegé, R. |
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Nucleic Acids Res., 1993, 21, 41-49 |
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| 25 |
"tRNA Structure and Aminoacylation Efficiency," Giegé, R., Florentz, C., & Puglisi, J. D., |
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Prog. Nucl. Acids Res. Molec. Biol., 1993, 45, 129-206 |
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| 24 |
"Structure and Function of HIV TAR RNA," Puglisi, J. D., Tan, R., Frankel, A. D., Williamson, J. R. |
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in Structural Tools for the Analysis of Protein-Nucleic Acid Complexes Advances in Life Sciences, 1992, D. Lilley, H. Heumann, D. Suck, eds., pp. 269-285 |
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| 23 |
"Preparation of Isotopically Labeled Ribonucleotides for Multidimensional NMR Spectroscopy of RNA," Batey, R. T., Inada, M., Kujawinski, E., Puglisi, J. D., & Williamson, J. R. |
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Nucleic Acids Res., 1992, 20, 4515-4523 |
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| 22 |
"Conformation of the TAR RNA-Arginine Complex by NMR Spectroscopy," Puglisi, J. D., Tan, R., Calnan, B. J.,Frankel, A. D. & Williamson, J. R. |
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Science, 1992, 257, 76-80 |
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| 21 |
"Effect of Conformational Features on the Aminoacylation of tRNAs and Consequences on the Permutation of tRNA Specificities," Perret, V., Florentz, C., Puglisi, J. D., & Giegé, R. |
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J. Mol. Biol., 1992, 226, 323-333 |
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| 20 |
"Determinant Nucleotides of Yeast tRNA Asp Interact Directly with Aspartyl-tRNA Synthetase," Rudinger, J., Puglisi, J. D., Pütz, J., Schatz, D., Eckstein, F., Florentz, C. & Giegé, R. |
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Proc. Natl. Acad. Sci. U.S.A., 1992, 89, 5882-5886 |
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| 19 |
"Synthesis and Purification of Large Amounts of RNA Oligonucleotides," Wyatt, J. R., Chastain, M. & Puglisi, J. D. |
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BioTechniques, 1991, 11, 764-769 |
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| 18 |
"Identity Elements for Specific Aminoacylation of Yeast tRNA Asp by Cognate Aspartyl-tRNA Synthetase," Pütz, J., Puglisi, J. D., Florentz, C. & Giegé, R. |
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Science, 1991, 252, 1696-1699 |
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| 17 |
"RNA Pseudoknots," Puglisi, J. D., Wyatt, J. R. & Tinoco, I., Jr |
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Accts Chem. Res., 1991, 24, 152-158 |
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| 16 |
"Conformation in Solution of tRNA Asp Transcripts Deprived of Modified Nucleotides," Perret, V., Garcia, A., Puglisi, J., Grosjean, H., Ebel, J.-P. & Giegé, R. |
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Biochimie, 1990, 72, 735-744 |
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| 15 |
"Exploring the Aminoacylation Function of transfer RNA by Macromolecular Engineering Approaches. Involvement of conformational features in the charging process of yeast tRNA Asp," Giegé, R., Florentz, C., Garcia, A., Grosjean, H., Perret, V., Puglisi, J., Theobald-Dietrich, A., & Ebel, J.-P. |
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Biochimie, 1990, 72, 735-747 |
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| 14 |
"Conformation of an RNA Pseudoknot," Puglisi, J. D., Wyatt, J. R. & Tinoco, I., Jr. |
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J. Mol. Biol., 1990, 214, 437-453 |
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| 13 |
"RNA Pseudoknots: Stability and Loop Size Requirements," Wyatt, J. R., Puglisi, J. D. & Tinoco, I., Jr. |
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J. Mol. Biol., 1990, 214, 455-470 |
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| 12 |
"Solution Conformation of an RNA Hairpin Loop," Puglisi, J. D., Wyatt, J. R. & Tinoco, I., Jr. |
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Biochemistry, 1990, 29, 4215-4226 |
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| 11 |
"RNA Folding," Tinoco, I. Jr., Puglisi, J. D. & Wyatt, J. R. |
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Nucleic Acids and Molecular Biology, 1990, 4, F. Eckstein & D. Lilley, eds., Springer-Verlag, Berlin, pp. 205-226 |
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| 10 |
"RNA Folding: Pseudoknots, Loops and Bulges," Wyatt, J. R., Puglisi, J. D. & Tinoco, I. Jr. |
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Bioessays, 1989, 11, 100-106 |
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| 9 |
"Nucleic Acids from A to Z," Tinoco, I.,Jr., Aboul-ela, F., Hardin, C.C., Puglisi, J.D., Varani, G.,Walker, G.T., Wolk, S. & Wyatt, J. R. |
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Frontiers of Macromolecular Science, 1989, T. Saegusa, T. Higashimura & A. Abe, eds. pp. 519- 524, Blackwell Scientific Publications, Oxford |
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| 8 |
"Absorbance Melting Curves of RNA," Puglisi, J. D. & Tinoco, I.,Jr. |
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Methods in Enzymology, RNA Processing 180, 1989, J. E. Dahlberg & J. N. Abelson, eds, Academic Press, New York, |
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| 7 |
"A Pseudoknotted RNA Oligonucleotide," Puglisi, J. D., Wyatt, J. R. & Tinoco, I.,Jr. |
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Nature, 1988, 331, 283-286 |
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| 6 |
"Pseudoknotted RNA Oligonucleotides," Wyatt, J. R., Puglisi, J. D.& Tinoco, I., Jr. |
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Molecular Biology of RNA, (T. Cech, ed.) U.C.L.A Symposia Series, 1988, 94, 25-32, Alan. R. Liss, Inc., New York, N.Y |
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| 5 |
"RNA Structure from A to Z," Tinoco, I., Jr., Davis, P.W., Hardin, C.C., Puglisi, J.D.,Walker, G.T. & Wyatt, J.R. |
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Cold Spring Harbor Symp. Quant. Biol., 1988, 52, 135-146 |
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| 4 |
"Raman Spectroscopic Study of Left-Handed Z-RNA," Trulson, M.O., Cruz, P., Puglisi, J.D., Tinoco, I., Jr. & Mathies, R.A. |
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Biochemistry, 1987, 26, 8624-8630 |
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| 3 |
"Stabilization of Z-RNA by chemical bromination and its recognition by anti-Z-DNA antibodies," Hardin, C.C., Zarling, D.A., Puglisi, J.D., Trulson, M. O., Davis, P.D. & Tinoco, I.,Jr. |
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Biochemistry, 1987, 26, 5191-5199 |
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| 2 |
"The Left-Handed Z-Form of Double-Stranded RNA," Cruz, P., Hall, K., Puglisi, J., Davis, P., Hardin, C., Trulson, M., Mathies, R., Tinoco, I.,Jr., Johnson, W.,Jr. & Neilson, T.1986 |
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Biomolecular Stereodynamics, IV, 1986, Adenine Press, New York , pp 179-200 |
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| 1 |
"Z-RNA: A Left-Handed Double Helix," Tinoco, I.,Jr., Cruz, P., Davis, P., Hall, K., Hardin, C.C., Mathies, R. A., Puglisi, J. D., Trulson, M. O., Johnson, W. C., & Neilson, T. |
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Structure and Dynamics of RNA, 1986, Plenum Press, New York, pp. 55-68 |
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Invited Talks and Seminars |
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Apr 1990 |
EMBO Workshop: DNA-Protein Interactions. Autrans, France. "RNA Pseudoknots" |
Apr 1996 |
Yale University, Dept of Molecular Biology and Biophysics. "Structural basis of aminoglycoside antibiotic action" |
Apr 1997 |
MRC Laboratory of Molecular Biology, Cambridge, U.K., "Structural basis for aminoglycoside antibiotic action" |
Apr 1997 |
NATO Advanced Study Institute, Protein Structure and Dynamics, Erice, Italy. "RNA structure and Function" |
Apr 1997 |
University of Brescia, Institute of Microbiology, Italy. "How Aminoglycoside Antibiotics Work" |
Apr 1998 |
Third European Conference on Stable Isotope Assisted NMR of biological Macromolecules, Oxford UK |
Apr 1999 |
The Johns Hopkins University, Dept of Molecular and Cellular Biology |
Apr 1999 |
Theoretical Course "RNA Structure and Function", Trieste, Italy |
Apr 2000 |
Varian Users Conference, Keynote address "NMR of RNAs large and small", Stanford University |
Apr 2001 |
Theoretical Course "RNA Structure and Function", Trieste, Italy |
Aug 1998 |
International Conference of Magnetic Resonance in Biological Systems. Tokyo |
Aug 1999 |
International Union of Crystallography, Glasgow, UK |
Aug 2000 |
"Structures of RNAs large and small", Florence, Italy |
Aug 2000 |
Workshop on Chemical Biology, Sandhamn, Sweden |
Aug 2001 |
222nd ACS National Meeting, Chicago, Illinois |
Dec 1991 |
Biomolecular Structure/Function Seminar. Massachusetts Institute of Technology. "RNA conformational flexibility" |
Feb 1991 |
Minisymposium on RNA Structure. University of Leiden, Netherlands |
Feb 1994 |
Keystone Symposium, Nucleic Acid-Protein Interactions, Tamarron, CO. "RNA Conformational Flexibility" |
Feb 1996 |
University of California, Riverside, Dept of Chemistry, "Structural basis of aminoglycoside antibiotic action" |
Feb 1997 |
Frontiers of NMR in Molecular Biology IV, Taos, NM, "How aminoglycoside antibiotics work" |
Feb 1997 |
Scripps Research Institute, Department of Chemistry, "RNA as a drug target" |
Feb 1997 |
Smith-Kline-Beecham Symposium, Cambridge, U. K., "RNA as a drug target" |
Feb 1998 |
Biophysical Society National Meeting, Kansas City, MO. |
Feb 1998 |
NMR in Biology Gordon Conference, Ventura, CA |
Jan 1997 |
Stanford University, Department of Structural Biology "Structural basis of aminoglycoside antibiotic action" |
Jan 1999 |
Ribo-Nucleic Acid Structure by Nuclear Magnetic Resonance, Paris, France |
Jan 2000 |
"N.M.R.: a tool for biology IV." Paris, France |
Jan 2001 |
"RNA and Translation", Keystone Symposia on Molecular & Cellular Biology, Montana |
Jul 1997 |
Nucleic Acid-Protein Interaction Symposium. The Biochemical Society Nat'l Meeting, Dundee, UK. "Structural origin of ligand-RNA interaction in the ribosome" |
Jul 1998 |
FEBS Silver Jubilee Meeting, Copenhagen, DK |
Jul 2001 |
Royal Society of Chemistry, "15th Int'l Meeting on NMR Spectroscopy", Durham, UK. |
Jun 1989 |
Gordon Conference-Nucleic Acids, New Hampton, N.H. "RNA Pseudoknots and Hairpins" |
Jun 1995 |
Gordon Conference-Nucleic Acids, New Hampton NH "Structural basis of aminoglycoside antibiotic action" |
Jun 1996 |
Gordon Conference-Biopolymers Newport, RI. "Structural basis of aminoglycoside antibiotic action" |
Jun 1999 |
Gordon Conference, "Computational Methods in NMR spectroscopy". Il Ciocco, Italy |
Jun 1999 |
Ribosome Meeting, 1999. Copenhagen, Denmark |
Jun 2000 |
"RNA Structure Symposium", Santa Cruz, CA |
Jun 2000 |
"Structure & Function of Ribosomal Nucleid Acids", Universite Paul Sabatier, Toulouse France |
Jun 2000 |
14th Annual Meeting of the Groups Studying the Structure of AIDS-Related Systems & their Application to Targeted, Bethesda, MD |
Jun 2001 |
Gordon Conference, "Virus & Cells", Tilton, NH |
Jun 2001 |
NATO Advanced Study Institute, "5th Course: Protein Structure, Dynamics, Genomics and Function", Erice, Italy |
Mar 1994 |
Institute of Microbiology, University of Brescia Medical School, Brescia, Italy. "Structure and function of HIV TAR RNA" |
May 1992 |
Structural Tools for the Analysis of Protein-Nucleic Acid Complexes. Wilbad-Kreuth, Germany "Structure and Function of HIV TAR" |
May 1994 |
Biophysics Group, University of California, San Francisco, CA. "RNA structure using NMR spectroscopy" |
May 1995 |
International Translation Workshop, Victoria, BC "Structural basis of aminoglycoside antibiotic action" |
May 1996 |
Buffalo Medicinal Chemistry Conference "RNA as a drug target" |
May 1997 |
ASPRONC Annual Meeting, RNA-protein systems, Tokyo, Japan. "Aminoglycoside-RNA interactions" |
May 1997 |
First Meeting of Yokoyama Cytologic Project, Tokyo, Japan. "tRNA-ribosome interactions" |
May 1998 |
NIH Meeting of Structural Biology of HIV, Washington, D.C. |
May 1999 |
NATO Advanced Study Institute, "Structure and Dynamics of Biological Macromolecules", Erice, Italy |
May 2000 |
"The structural basis for aminoglycoside antibiotic action", Georgia Tec Institute, Atlanta |
Nov 1990 |
Department of Biochemistry, University of Dundee, UK. "RNA Pseudoknots and Hairpins" |
Nov 1996 |
California Institute of Technology, Department of Chemistry, "Structural basis of aminoglycoside antibiotic action" |
Nov 1998 |
National Institutes of Health, Laboratory of Chemical Physics |
Oct 1989 |
Institut de Biologie Moleculaire et Cellulaire du CNRS, Strasbourg, France. "Structure and Stability of RNA Pseudoknots" |
Oct 1992 |
Biomolecular Structure/Function Seminar. Massachusetts Institute of Technology. "Structure and Function of HIV TAR" |
Oct 1993 |
Bay Area RNA Club, San Francisco, CA. "Structure of HIV TAR RNA" |
Oct 1997 |
Stanford University, Dept. of Chemistry. "RNA as a drug target" |
Oct 1997 |
Wayne State University, Dept of Chemistry. Student-Invited Lecturer |
Oct 1999 |
Tsakuba NMR 1999. Tsakuba, Japan |
Oct 2000 |
"How aminoglycoside antibiotics work", Eccles Institute of Human Genetics University of Utah |
Sep 2000 |
"Structural Aspects of Protein Synthesis", Rensslaerville, New York |
Sept 1996 |
University of California, Berkeley. Structural Biology Seminar, "RNA as a drug target" |
Sept 1997 |
American Chemical Society Nat'l Meeting. Las Vegas, NV. "RNA-drug interaction" |
Sept 1997 |
Structural Aspects of Protein Synthesis, Tallberg, Sweden. "Structure of rRNA domains" |
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