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Human immunodeficiency virus 1 5′-leader mutations in plasma viruses before and after the development of reverse transcriptase inhibitor-resistance mutations

Nouhin J, Tzou PL, Rhee SY, Sahoo MK, Pinsky BA, Krupkin M, Puglisi JD, Puglisi EV, Shafer RW. Human immunodeficiency virus 1 5′-leader mutations in plasma viruses before and after the development of reverse transcriptase inhibitor-resistance mutations. J Gen Virol. […]
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Partial spontaneous intersubunit rotations in pretranslocation ribosomes

Huang T, Choi J, Prabhakar A, Puglisi JD, Petrov A. Partial spontaneous intersubunit rotations in pretranslocation ribosomes. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2114979120. doi: 10.1073/pnas.2114979120. Epub 2023 Oct 6. PMID: 37801472.
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Universal features of Nsp1-mediated translational shutdown by coronaviruses

Schubert K, Karousis ED, Ban I, Lapointe CP, Leibundgut M, Bäumlin E, Kummerant E, Scaiola A, Schönhut T, Ziegelmüller J, Puglisi JD, Mühlemann O, Ban N. Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol Cell. 2023 Oct 5;83(19):3546-3557.e8. doi: […]
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Real-time detection of human telomerase DNA synthesis by multiplexed single-molecule FRET

Hentschel J, Badstübner M, Choi J, Bagshaw CR, Lapointe CP, Wang J, Jansson LI, Puglisi JD, Stone MD. Real-time detection of human telomerase DNA synthesis by multiplexed single-molecule FRET. Biophys J. 2023 Jul 27:S0006-3495(23)00471-X. doi: 10.1016/j.bpj.2023.07.019. PMID: 37515327.
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Pressure pushes tRNALys3 into excited conformational states

Wang J, Koduru T, Harish B, McCallum SA, Larsen KP, Patel KS, Peters EV, Gillilan RE, Puglisi EV, Puglisi JD, Makhatadze G, Royer CA. Pressure pushes tRNALys3 into excited conformational states. Proc Natl Acad Sci U S A. 2023 Jun […]
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Dynamics of release factor recycling during translation termination in bacteria

Prabhakar A, Pavlov MY, Zhang J, Indrisiunaite G, Wang J, Lawson MR, Ehrenberg M, Puglisi JD. Dynamics of release factor recycling during translation termination in bacteria. Nucleic Acids Res. 2023 Apr 27:gkad286. doi: 10.1093/nar/gkad286. PMID: 37102635.
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