The groups of Jody Puglisi and Elisabetta Viani Puglisi investigate the physical basis for RNA function in biology. We apply biochemical, structural and biophysical approaches to link three-dimensional structures of RNAs and their complexes with their dynamics.
Rosslyn Grosely, Carlos Alvarado, et al. eIF1 and eIF5 dynamically control translation start site fidelity. Nat Struct Mol Biol. 2025 Jul 28:10.1038/s41594-025-01629-y. doi: 10.1038/s41594-025-01629-y. PMID: 40721534.
Michael Palo, Betty Ha, Christopher Lapointe, et al. Conserved long-range interactions are required for stable folding of orthoflaviviral genomic RNA. Nucleic Acids Res. 2025 Jun 24:gkaf514. doi: 10.1093/nar/gkaf514. PMID: 40521663.
Crystal and Ajinkya passed their qualifying exams!
Lab alum Albert Tsai will join the Montpellier Cell Biology Research Center as a Group Leader! Follow his research at his website or on Twitter @altsaiphys