Research Highlights

The groups of Jody Puglisi and Elisabetta Viani Puglisi investigate the physical basis for RNA function in biology. We apply biochemical, structural and biophysical approaches to link three-dimensional structures of RNAs and their complexes with their dynamics.

Recent Publications

Arjun Prabhakar, Michael Pavlov, Jingji Zhang, et al. Dynamics of release factor recycling during translation termination in bacteria. Nucleic Acids Res. 2023 Apr 27:gkad286. doi: 10.1093/nar/gkad286. PMID: 37102635.

Jinfan Wang, Byung-Sik Shin, Carlos Alvarado, et al. Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation. Cell. 2022 Nov 23. doi: 10.1016/j.cell.2022.10.005. PMID: 36334590.

Arjun Prabhakar, Natalie Krahn, Jingji Zhang, et al. Uncovering translation roadblocks during the development of a synthetic tRNA. Nucleic Acids Res. 2022 Oct 14;50(18):10201-10211. doi: 10.1093/nar/gkac576. PMID: 35882385.

Lab News

Lab alum Albert Tsai will join the Montpellier Cell Biology Research Center as a Group Leader! Follow his research at his website or on Twitter @altsaiphys

Jinfan Wang will join the Department of Biochemistry at UT Southwestern Medical Center as an Assistant Professor in September, 2023!

Chris Lapointe will join the Basic Sciences Division at the Fred Hutchinson Cancer Center as an Assistant Professor on July 1, 2023!

Mike Lawson will be starting as an Assistant Professor at UCLA Chemistry & Biochemistry on July 1st, 2023!